rac-3-[(Anilino)(naphthalen-2-yl)­methyl]thian-4-one

Application of N-methylimidazole for the Synthesis of Dimethyl-{3-methyl-2-[(alkoxycarbonyl) anilino]-2,3-dihydro-1H-imidazol-1-yl)}-2-butenedioate Derivatives

A one-pot synthesis ofdimethyl-{3-methyl-2-[(alkoxycarbonyl) anilino]-2,3-dihydro-1Himidazol-1-yl)}-2-butenedioatesanddimethyl-2-[(alkoxycarbonyl)anilino]-2-butenedioates derivatives via reactions between dimethyl acetylenedicarboxylate,1-methylimidazoleand N-phenylcarbamates is described. The mild reaction condition, simple mixing of the starting materials and good yields exhibit the synthetic...

Synthesis, anti-inflammatory and analgesic evaluation of thioxoquinazolinone derivatives.

A series of 3-substituted-2-thioxoquinazolin-4(3H)-one derivatives have been synthesized and their structures have been elucidated on the basis of IR, (1)H-NMR, elemental analysis and mass spectroscopic studies. Anti-inflammatory and analgesic activity of the synthesized compounds was evaluated by Carrageenan induced rat paw edema method and Eddy's hot plate method respectively. Among the synth...

(S)-3-[(S,E)-4-(4-Chloro­phen­yl)-1-nitro­but-3-en-2-yl]thian-4-one

The title compound, C(15)H(16)ClNO(3)S, was obtained by the organocatalytic asymmetric Michael addition of thian-4-one to 1-chloro-4-[(1E,3E)-4-nitro-buta-1,3-dien-yl]benzene. The double bond has an E configuration and the thian-4-one six-membered ring adopts a chair conformation. The crystal structure is stabilized by weak inter-molecular C-H⋯O hydrogen bonds.

Discussion Word Count: 6,671 Abbreviations and definitions: ACPU, 1-(Adamantan-1-yl)-3-(1-(2-(7-hydroxy-2-oxo-2H-chromen- 4-yl)acetyl)piperidin-4-yl)urea; ARDS, Acute Respiratory Distress Syndrome; AUDA, 12-(3- Adamantan-1-yl-ureido)-dodecanoic acid; CDU, 1-cyclohexyl-3-dodecyl urea; ChEH, Cholesterol Epoxide Hydrolase; CMNPO, Cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-

Bis(1-methyl-1H-imidazole-κN 3)bis­[2-(naphthalen-1-yl)acetato-κO]copper(II) monohydrate

In the crystal structure of the title compound, [Cu(C(12)H(9)O(2))(2)(C(4)H(6)N(2))(2)]·H(2)O, the Cu(II) atom is coordinated by two 2-(naphthalen-1-yl)acetate anions and two 1-methyl-imidazole ligands, giving monomeric complexes with a square-planar coordination environment. Two complex mol-ecules and two water mol-ecules form a centrosymmetric ring system via O-H⋯O hydrogen bonds.